Product Name :
Motesanib Diphosphate (AMG-706)
CAS No.:
857876-30-3
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3.O[P](O)(O)=O.O[P](O)(O)=O
Product Description :
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.
Formula:
C22H29N5O9P2
Molecular Weight :
569.44
Synonyms:
Additional Information:
|CAS No. 857876-30-3 ; |Formula C22H29N5O9P2 ; |Molecular Weight 569.44 ; |SMILES CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3.O[P](O)(O)=O.O[P](O)(O)=O ; |Product Description Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.GDC-6599 Phase 3.RNase Inhibitor ; |Purity > 99% ; |Shipping Shipped on dry ice.PMID:25105126 ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO