About US

SFRP1 (Secreted frizzled-associated protein 1) is a protein which in individuals is encoded by the SFRP1 gene.Secreted frizzled-associated protein 1 (SFRP1) is a member of the SFRP relatives that consists of a cysteine-prosperous domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. counteracting Wnt-induced consequences at substantial concentrations and promoting them at reduced concentrations. Secreted Frizzled-linked protein 1 (SFRP1) is a adverse regulator of the Wnt pathway. It has been described that SFRP1 mRNA is strongly down-controlled in breast most cancers and a putative tumor suppressor perform has been postulated.