Ood Bioprod Course of action 2003, 81:81?eight. 31. St l K, Claesson M, Lilliehorn P, Lind H, B kstr K: The effect of process variables around the degradation and physical properties of spray dried insulin intended for inhalation. Int J Pharm 2002, 233:227?37. 32. Vehring R: Pharmaceutical particle engineering by way of spray drying. Pharm Res 2008, 25:999?022. 33. LechugaBallesteros D, Charan C, Stults CL, Stevenson CL, Miller DP, Vehring R, Tep V, Kuo MC: Trileucine improves aerosol performance and stability of spraydried powders for inhalation. J Pharm Sci 2008, 97:287?02. 34. Srichana T, Brain A, Marriott C, Martin GP: A study of drug-carrier interactions in dry powder inhaler formulations applying the Andersen cascade impactor, X-ray microanalysis and time of flight aerosol beam spectrometry (TOFABS). Chem Pharm Bull 2000, 48:167?74. 35. Scalia S, Salama R, Young P, Traini D: Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. J Microencap 2012, 29:225?33.Daman et al. DARU Journal of Pharmaceutical Sciences 2014, 22:50 darujps/content/22/1/Page 9 of36. Yu J, Chien YW: Pulmonary drug delivery: physiologic and mechanistic aspects. Crit Rev Ther Drug Carrier Syst 1997, 14:395?53. 37. Bosquillon C, Lombry C, Preat V, Vanbever R: Comparison of particle sizing strategies in the case of inhalation dry powders. J Pharm Sci 2001, 90:2032?041. 38. Zeng XM, Martin GP, Marriott C: Particulate Interactions in Dry Powder Formulation for Inhalation. London: Taylor Francis; 2000.doi:10.1186/2008-2231-22-50 Cite this short article as: Daman et al.: Formulation of inhalable lipid-based salbutamol sulfate microparticles by spray drying strategy. DARU Journal of Pharmaceutical Sciences 2014 22:50.Submit your next manuscript to BioMed Central and take complete benefit of:?Handy on the net submission ?Thorough peer evaluation ?No space constraints or colour figure charges ?Immediate publication on acceptance ?Inclusion in PubMed, CAS, Scopus and Google Scholar ?Study which is freely available for redistributionSubmit your manuscript at biomedcentral/submit
Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA) is usually a phenolic acid that’s found abundantly within the hemicellulose of plant cell walls, where it cross-links CA125 Protein custom synthesis arabinoxylan molecules through arabinose residues, along with other individuals, inside the Poaceae plant family. FA has potential therapeutic applications on account of its antioxidant and anti-inflammatory properties [1]. FA moderates oxidative anxiety and inflammation in Alzheimer’s illness [2,3] as well as reduces DNA harm from irradiation in mammalian cells [4]. FA is also applied to create the flavoring agent vanillin by microbial conversion [5,6]. Enzymatic production of FA from biomass has been reported previously [7,8], and feruloyl Angiopoietin-2 Protein Formulation esterase (FAE) has been identified as a important enzyme inside the process [9]. FAE is located in Aspergillus species including A. niger [10], A. awamori [11,12], along with a. oryzae [13]. FAEs are classified into four subgroups, A, B, C, and D, based on their amino acid sequences and substrate specificity [13]. Additionally, FAEs from Streptomyces species have also been reported [14,15], however, genetic information and facts on Streptomyces FAEs relative to FAE activity is still unclear.Streptomyces is often a widely made use of bacterium and also the genomic sequences of a number of Streptomyces species happen to be identified [16,17]. A number of genes that code for beneficial enzymes have been identified inside the Streptomyces genome which can be.