Outine care23.Beral et al. [70]Case reportVAC24.SiomaMarkowska U. [79]Case seriesAutolytic debridement lavasepsis metalliccoated SDDirect postoperative application to the surgical internet site Statistical evaluation Wilcoxon rank sum test, Fisher precise test, wound NIMA Related Kinase 3 Proteins Recombinant Proteins closure prices evaluated with KaplanMeier survival estimateNo. 1.Outcomes 29 14 days of therapy in remedy group vs. 47 24 days in handle group (p = 0.057); total wound closure soon after 35 15 days of therapy in therapy group vs. 54 26 days in control group (p = 0.05); additional speedy wound closure in treatment group Important reduction in discomfort on postoperative day 0 and 1 (p B 0.001); significant reduction in total dose of morphine (p = 0.02) Significant lower in wound infection, necrosis and breakdown prices (p = 0.032; p = 0.096; p = 0.048, respectively); substantial reduce in postoperative fever price and hospital stay (p \ 0.001); total wound closure just after 24 days of therapy in study group vs. 93 days in control group (p \ 0.001) Key wound healing ADAMTS20 Proteins Formulation observed in 69.7 of vulva and groin wounds in study group vs. 25 in manage group; big wound breakdown observed in 6.1 of vulva and groin wounds in study group vs. 50 in handle groupComplications NA2.Fanning et al. [37]Follow-up on day 7 and 28 postoperatively; nobody lost to follow-upNo adverse effects observedChi-square test, Fisher precise test, Student t test3.Morelli et al. [43]NANAChi-square test, Fisher exact test, Student t test4.van Lindert et al. [44]Follow-up on day five and 10 postoperatively; nobody lost to follow-upMajor wound breakdown or skin separation observed in 6.1 and 15.1 of vulva and groin wounds, respectivelyNA764 Table 1 continued No. 5. References Uyl-de Groot et al. [45] Outcomes No significant differences observed with respect to wound infection and principal wound healing rates; no significant differences observed with respect to top quality of life; total remedy expense in study group EUR 15,951 vs. manage group EUR 12,430 P1: substantial decrease in wound volume after 14 days of therapy; total wound closure four weeks postdischarge P2: substantial decrease in wound volume just after ten days of therapy; comprehensive wound closure P3: significant lower in wound volume just after 13 days of therapy, fistula closure on day 7 of therapy; complete wound closure In all individuals enhanced granulation tissue formation was observed inside the initial 48 h of VAC therapy 7. 8. Miller et al. [54] Stannard et al. [55] Wound closure just after 3 months; no analgesics expected P1: total wound closure just after 4 weeks P2: uncomplicated wound healing 9. 10. Gourgiotis et al. [56] Lavoie et al. [57] Complete fascial closure just after 21 days 7 days of therapy; patient discharge following 36 days following debridement; complete wound closure just after 82 days following debridement; no skin grafting required 96 reduction within the median size of wound defect; median VAC therapy length 32 days (range 38 days); at the time of final speak to 26 of 27 patients presented total wound healing Median VAC therapy length 11 days (variety 68 days); total wound closure soon after 44 18 days of therapy in study group vs. 60 29 days in control group (p = 0.0175); no considerable difference in length of hospital stay 3 months 2 months three months P1: 4 weeks postoperatively P2: 4 days postoperatively NA Follow-up Follow-up on day 30 and 56 postoperatively; 1 patient in study group excluded; three patients in study group lost to follow-upArch Gynecol Obstet (2015) 292:.