E. A part of his explanation for the error was his willingness to capitulate when tired: `I didn’t ask for any health-related history or anything like that . . . more than the phone at three or 4 o’clock [in the morning] you simply say yes to anything’ pnas.1602641113 Interviewee 25. In spite of sharing these comparable characteristics, there were some differences in error-producing conditions. With KBMs, medical doctors have been conscious of their information deficit at the time with the prescribing decision, unlike with RBMs, which led them to take one of two pathways: approach other individuals for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures inside healthcare teams prevented doctors from seeking support or indeed receiving adequate support, highlighting the importance from the prevailing medical culture. This varied amongst specialities and accessing guidance from seniors appeared to become extra problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for assistance to prevent a KBM, he felt he was annoying them: `Q: What created you think which you might be annoying them? A: Er, just because they’d say, you know, very first words’d be like, “Hi. Yeah, EED226 web what’s it?” you understand, “I’ve scrubbed.” That’ll be like, sort of, the introduction, it would not be, you understand, “Any challenges?” or anything like that . . . it just doesn’t sound really approachable or Eliglustat friendly around the telephone, you understand. They just sound rather direct and, and that they were busy, I was inconveniencing them . . .’ Interviewee 22. Medical culture also influenced doctor’s behaviours as they acted in approaches that they felt have been essential so as to fit in. When exploring doctors’ motives for their KBMs they discussed how they had selected not to seek suggestions or data for worry of seeking incompetent, particularly when new to a ward. Interviewee 2 below explained why he did not check the dose of an antibiotic despite his uncertainty: `I knew I should’ve looked it up cos I didn’t genuinely know it, but I, I feel I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was one thing that I should’ve identified . . . because it is very uncomplicated to obtain caught up in, in becoming, you understand, “Oh I’m a Physician now, I know stuff,” and with all the stress of individuals who’re perhaps, sort of, somewhat bit more senior than you thinking “what’s incorrect with him?” ‘ Interviewee 2. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent situation instead of the actual culture. This interviewee discussed how he ultimately discovered that it was acceptable to check data when prescribing: `. . . I locate it rather good when Consultants open the BNF up in the ward rounds. And also you think, properly I am not supposed to know each single medication there is certainly, or the dose’ Interviewee 16. Medical culture also played a part in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior doctors or skilled nursing staff. A very good instance of this was offered by a medical professional who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, despite having currently noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and mentioned, “No, no we should really give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it around the chart without the need of considering. I say wi.E. Part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any medical history or anything like that . . . over the phone at three or 4 o’clock [in the morning] you just say yes to anything’ pnas.1602641113 Interviewee 25. Regardless of sharing these equivalent traits, there have been some differences in error-producing circumstances. With KBMs, physicians had been conscious of their knowledge deficit at the time on the prescribing selection, unlike with RBMs, which led them to take certainly one of two pathways: strategy other folks for314 / 78:two / Br J Clin PharmacolLatent conditionsSteep hierarchical structures within medical teams prevented doctors from seeking aid or indeed receiving adequate support, highlighting the importance of the prevailing healthcare culture. This varied in between specialities and accessing guidance from seniors appeared to be far more problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for tips to stop a KBM, he felt he was annoying them: `Q: What produced you think which you may be annoying them? A: Er, just because they’d say, you realize, 1st words’d be like, “Hi. Yeah, what’s it?” you know, “I’ve scrubbed.” That’ll be like, sort of, the introduction, it wouldn’t be, you realize, “Any challenges?” or anything like that . . . it just does not sound pretty approachable or friendly around the telephone, you realize. They just sound rather direct and, and that they had been busy, I was inconveniencing them . . .’ Interviewee 22. Healthcare culture also influenced doctor’s behaviours as they acted in methods that they felt were needed as a way to match in. When exploring doctors’ causes for their KBMs they discussed how they had selected to not seek assistance or information for fear of searching incompetent, in particular when new to a ward. Interviewee two below explained why he didn’t check the dose of an antibiotic in spite of his uncertainty: `I knew I should’ve looked it up cos I did not genuinely know it, but I, I consider I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was something that I should’ve known . . . because it is quite effortless to acquire caught up in, in becoming, you realize, “Oh I’m a Doctor now, I know stuff,” and using the stress of folks who are perhaps, kind of, somewhat bit a lot more senior than you pondering “what’s incorrect with him?” ‘ Interviewee 2. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent situation as an alternative to the actual culture. This interviewee discussed how he ultimately discovered that it was acceptable to verify data when prescribing: `. . . I come across it pretty good when Consultants open the BNF up within the ward rounds. And you think, effectively I’m not supposed to know every single single medication there is, or the dose’ Interviewee 16. Healthcare culture also played a role in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior physicians or seasoned nursing employees. A superb example of this was provided by a medical professional who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, regardless of having already noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and said, “No, no we must give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart devoid of thinking. I say wi.