The development of effective strategies to combat multidrug-resistant (MDR) cancers remains a critical challenge in oncology. In this study, a series of amino-acid-functionalized perylene diimide (PDI-AA) derivatives—PDI-Asp, PDI-Ala, and PDI-5AVA—were…
Inflammatory bowel disease (IBD) remains a significant clinical challenge due to the need for long-term, targeted therapy with minimal systemic exposure. Berberine (BBR), a natural alkaloid with potent anti-inflammatory and…
The synthesis and structural characterization of pyrazine-pillared metal-organic frameworks (MOFs) derived from the ligand substitution of Group 6 metal hexacarbonyls—Cr(CO)₆, Mo(CO)₆, and W(CO)₆—are reported. The reaction of these homoleptic carbonyl…
The adsorption mechanism of Cr(VI) and methyl orange (MO) on the citric acid-crosslinked Zn-MOF/chitosan (ZnBDC/CSC) composite was systematically investigated based on spectroscopic, kinetic, and thermodynamic analyses. At pH 5.0, Cr(VI)…
The concept of porous liquids, first introduced by James in 2007, represents a revolutionary advancement in materials science by merging the structural rigidity of porous solids with the fluidity of…
Baicalein and scutellarein are bioactive flavonoids derived from Scutellaria baicalensis Georgi, known for their antioxidant, antitumor, and anti-inflammatory properties. Despite their therapeutic potential, efficient microbial production remains challenging due to…
The incorporation of high amylose corn starch (HAS)-fatty acid complexes into Nemipterus virgatus surimi significantly enhances gel properties, protein secondary structure, microstructure, fatty acid content, and sensory attributes when subjected…
Polyethylene microplastics were artificially aged using xenon light to simulate natural weathering processes. This study investigated the changes in surface structure, chemical properties, and adsorption-desorption behavior of these microplastics when…
Lamellar macular hole (LMH) is a partial-thickness foveal defect characterized by an irregular foveal contour, undermined edges, and loss of retinal tissue. Recent advances in spectral-domain optical coherence tomography (OCT)…
The programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) signaling pathway plays a pivotal role in immune regulation and has emerged as a key target for cancer immunotherapy. Blockade of…