Product Name :
E3 ligase Ligand 9
Description:
E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
CAS:
87304-15-2
Molecular Weight:
408.49
Formula:
C21H32N2O6
Chemical Name:
(2S)-2-[(2S,3R)-3-[(tert-butoxy)carbonyl]amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
Smiles :
CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](CC1C=CC=CC=1)NC(=O)OC(C)(C)C)C(O)=O
InChiKey:
DLADKYKXROHIAB-IKGGRYGDSA-N
InChi :
InChI=1S/C21H32N2O6/c1-13(2)11-16(19(26)27)22-18(25)17(24)15(12-14-9-7-6-8-10-14)23-20(28)29-21(3,4)5/h6-10,13,15-17,24H,11-12H2,1-5H3,(H,22,25)(H,23,28)(H,26,27)/t15-,16+,17+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Fingolimod Autophagy
Shelf Life:
≥12 months if stored properly.Probenecid Purity & Documentation
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32378438
Additional information:
E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.|Product information|CAS Number: 87304-15-2|Molecular Weight: 408.49|Formula: C21H32N2O6|Chemical Name: (2S)-2-[(2S,3R)-3-[(tert-butoxy)carbonyl]amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid|Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](CC1C=CC=CC=1)NC(=O)OC(C)(C)C)C(O)=O|InChiKey: DLADKYKXROHIAB-IKGGRYGDSA-N|InChi: InChI=1S/C21H32N2O6/c1-13(2)11-16(19(26)27)22-18(25)17(24)15(12-14-9-7-6-8-10-14)23-20(28)29-21(3,4)5/h6-10,13,15-17,24H,11-12H2,1-5H3,(H,22,25)(H,23,28)(H,26,27)/t15-,16+,17+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.Products are for research use only. Not for human use.|