Name :
HLA-A/B2M/KRAS G12V Monomer (Human) Recombinant Protein
Biological Activity :
Human HLA-A | B2M | KRAS G12V Tetramer (NP_002107.3 | P61769 | P01116, Gly25-Thr305 | Ile21-Met119 | VVVGAVGVGK) partial recombinant protein with His-Avi tag at C-terminus expressed in HEK293 cells.Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro
Tag :
Result of bioactivity analysis
Protein Accession No. :
NP_002107.3(HLA-A*03:01) | P61769(B2M) | VVGAVGVGK
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=567
Amino Acid Sequence :
Gly25-Thr305 | Ile21-Met119 | VVVGAVGVGK
Molecular Weight :
50.2
Storage and Stability :
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.Aliquot to avoid repeated freezing and thawing.
Host :
Human
Interspecies Antigen Sequence :
Preparation Method :
Mammalian cell (HEK293) expression system
Purification :
Quality Control Testing :
SEC-HPLC and Tris-Bis PAGE SEC-HPLC The purity of Human HLA-A*03:01 & B2M & KRAS G12V (VVVGAVGVGK) Monomer is greater than 95% as determined by SEC-HPLC. Tris-Bis PAGE Human HLA-A*03:01 & B2M & KRAS G12V (VVVGAVGVGK) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Storage Buffer :
Lyophilized from sterile distilled Water is > 100 ug/mL
Applications :
Functional Study， SDS-PAGE， Surface Plasmon Resonance， Human HLA-A*03:01 & B2M & KRAS G12V (VVVGAVGVGK) Monomer, His Tag captured on CM5 Chip via anti-his antibody can bind Anti-HLA-A*03:01 & B2M & KRAS G12V (VVVGAVGVGK) Antibody with an affinity constant of 0.11 uM as determined in SPR assay (Biacore T200).
Gene Name :
B2M
Gene Alias :
–
Gene Description :
beta-2-microglobulin
Gene Summary :
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia
Other Designations :
beta chain of MHC class I molecules|beta-2-microglobin
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