Product Name :
MK-8353 (SCH900353)

CAS No.:
1184173-73-6

Purity :
> 99%

Shipping:
Shipped on dry ice.

Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month

SMILES:
CSC1(CCN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=N[N](C)C=N4)C1)C(=O)NC5=CC=C6[NH]N=C(C7=CC=C(OC(C)C)N=C7)C6=C5

Product Description :
MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK inhibitor that inhibits activated ERK1 and ERK2 in vitro, with IC50 values of 23.0 nM and 8.8 nM, respectively (IMAP kinase assay), and nonactivated ERK2, with an IC50 of 0.5 nM (MEK1-ERK2-coupled assay).

Formula:
C37H41N9O3S

Molecular Weight :
691.84

Synonyms:

Additional Information:
|CAS No.Asciminib 1184173-73-6 ; |Formula C37H41N9O3S ; |Molecular Weight 691.Wogonin 84 ; |SMILES CSC1(CCN(CC(=O)N2CCC(=CC2)C3=CC=C(C=C3)C4=N[N](C)C=N4)C1)C(=O)NC5=CC=C6[NH]N=C(C7=CC=C(OC(C)C)N=C7)C6=C5 ; |Product Description MK-8353 (SCH900353) is an orally bioavailable, selective, and potent ERK inhibitor that inhibits activated ERK1 and ERK2 in vitro, with IC50 values of 23.PMID:23672196 0 nM and 8.8 nM, respectively (IMAP kinase assay), and nonactivated ERK2, with an IC50 of 0.5 nM (MEK1-ERK2-coupled assay). ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO

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