Product Name :
LY2874455
CAS No.:
1254473-64-7
Purity :
> 99%
Shipping:
Shipped on dry ice.
Storage :
Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month
SMILES:
CC(OC1=CC=C2[NH]N=C(\C=C\C3=C[N](CCO)N=C3)C2=C1)C4=C(Cl)C=NC=C4Cl
Product Description :
LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM.Mirvetuximab Phase 1.Vitamin D2
Formula:
C21H19Cl2N5O2
Molecular Weight :
444.PMID:23415682 31
Synonyms:
Additional Information:
|CAS No. 1254473-64-7 ; |Formula C21H19Cl2N5O2 ; |Molecular Weight 444.31 ; |SMILES CC(OC1=CC=C2[NH]N=C(\C=C\C3=C[N](CCO)N=C3)C2=C1)C4=C(Cl)C=NC=C4Cl ; |Target VEGFR2 ; |Product Description LY2874455 is a pan-FGFR inhibitor with IC50 of 2.8 nM, 2.6 nM, 6.4 nM, and 6 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively, and also inhibits VEGFR2 activity with IC50 of 7 nM. Phase 1. ; |Purity > 99% ; |Shipping Shipped on dry ice. ; |Storage Powder: -20 °C, 3 years; 4 °C, 2 yearsIn solvent: -80 °C, 6 months; -20 °C, 1 month ; |Solubility Overview Soluble in DMSO