Product Name: EGFR/HER1 Rabbit MAb
Immunogen: Recombinant Human EGFR / HER1 / ErbB1 Protein
Mouse IgG1: Rabbit IgG
Concentration:
Formulation: 0.2 μm filtered solution in Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0
Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR / HER1 / ErbB1 and was produced using recombinant antibody technology.
Specificity: Human EGFR / HER1 / ErbB1Has cross-reactivity with Rhesus EGFR (Catalog # 90317-K08H) in ELISA assayNo cross-reactivity with Mouse EGFR (Catalog # 51091-M08H) and Rat EGFR (Catalog # 80100-R08H) in ELISA assay
Application: NeutralizationIn a functional ELISA which immobilized the recombinant Human EGF (Catalog # 10605-H01H) at 2 μg/mL (100 μl/well) , 1 μg/mL of the Human EGFR antibody (Catalog # 10001-REN01) can blocked > 50% the binding of recombinant receptor EGFR (Catal
CAS NO.: 1633044-56-0
Product: FIIN-2
Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (
Caption: Cell Proliferation Induced by Autocrine EGF was Neutralized by Human EGFR Antibody. Autocrine EGF stimulates proliferation in the human breast cancer MDA-MB-468 cell line. Proliferation elicited by Autocrine EGF is neutralized by increasing concentrations
Background: As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role i
PubMed ID:http://jpet.aspetjournals.org/content/202/1/199